2016/17 Taught Postgraduate Module Catalogue

BIOL5262M Molecular Diagnostics and Drug Delivery

10 creditsClass Size: 40

Module manager: Dr Lars Jeuken
Email: L.J.C.Jeuken@leeds.ac.uk

Taught: Semester 2 (Jan to Jun) View Timetable

Year running 2016/17

Pre-requisite qualifications

Undergraduate degree in the biological sciences

Module replaces

BIOL5261M Molecular Diagnostics and Drug DeliveryBIOL5259M Novel Therapies

This module is not approved as an Elective

Module summary

This module covers the following topics; biosensors, drug delivery, molecular diagnostics and therapy. The molecular diagnostics component will be delivered by external industrial speakers from a range of biotechnology/bioscience companies, covering plant, environmental, clinical and food diagnostics. Assessment will be through an oral presentation relating to the molecular diagnostics component and a literature review associated with the biosensors/drug delivery/therapy component.

Objectives

On completion of this module, students should be able
- To provide an up to date understanding of biosensors including current and next-generation biosensors and biosensor design.
- To provide an up to date understanding of a variety of molecular diagnostic approaches used in a range of settings; including plant, environmental, medical and food areas.
- To provide an up to date understanding of the next-generation therapeutics, including those based on RNAi therapy or pharmaceutical which employ targeted drug delivery approaches.

Learning outcomes
On completion of this module, students should have:
- a full knowledge of the range of biosensor designs, the principal ways in which they can be interrogated, and an understanding of their current and potential applications in diagnostics and guide therapy.
- a clear understanding on how biosensors are integrated in industry for diagnostic purposed and have an understanding of some of the roles (molecular) diagnostics play in environmental, food and clinical companies.
- a good understanding of current research in drug delivery, drug design, including RNAi and how this might affect the next-generation pharmaceuticals and therapies.
- an understanding of employability prospects and how a (industrial) career can be built in diagnostics or pharmaceutical development
- the presentation skills (oral and writing) to communicate the knowledge described above.

Syllabus

- Introduction to biosensors.
- Introduction how biosensors are used in diagnostics
- Introduction how diagnostics influences pharmaceutical development and theory
- Introduction to RNA aptamers
- Introduction to drug delivery (polymers and liposomes)
- Introduction to new anti-bacterial drugs

Teaching methods

Delivery type	Number	Length hours	Student hours
presentation	1	2.00	2.00
Lecture	9	1.00	9.00
Seminar	6	1.50	9.00
Private study hours			80.00
Total Contact hours			20.00
Total hours (100hr per 10 credits)			100.00

Private study

Students should note that the following information is for guidance only. The actual time required for the various elements will vary between students.

- 3 hours of self-study per lecture (27 hours)
- 2 hour self-study per seminar (12 hours)
- 12 hours preparation oral presentation (12 hours)
- 29 hours - coursework (literature review) preparation.

Opportunities for Formative Feedback

Progress will be monitored during the seminars by joining in with Q&A session with the external speakers and through feedback provided at the oral presentation session.

Methods of assessment

Coursework

Assessment type	Notes	% of formal assessment
Literature Review	2000 words. Title will be given to student	70.00
Presentation	15 min. presentation. Two or three students will work together to prepare presentation. Topic will be given to students/couples.	30.00
Total percentage (Assessment Coursework)		100.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading list

The reading list is available from the Library website

Last updated: 26/07/2016

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