2016/17 Taught Postgraduate Module Catalogue

CAPE5310M Chemical Process Technology and Design

30 creditsClass Size: 30

Module manager: Professor J Blacker
Email: j.blacker@leeds.ac.uk

Taught: Semesters 1 & 2 (Sep to Jun) View Timetable

Year running 2016/17

Module replaces

PEME5305M Process Chemistry and Chemical Technology

This module is not approved as an Elective

Module summary

- Fundamentals of the chemical and process industries including the role of process chemists and engineers and intellectual property.- Introduction to synthetic chemistry route selection and the use of decision matrix analysis; chemical reactions, moles and yield; stereochemical issues in pharmaceutical materials, major synthetic pathways, types of reagents.- Basic principles of industrial process chemistry: process analysis, reagent selection, solvent selection, reaction conditions; batch and continuous processes, case study - batch manufacture of aspirin and drugs such as rosuvastatin, maraviroc or saxagliptin.- Basic principles of process economics: raw materials, catalysts, operational, capital costing; profit/loss, return on investment (ROI) and plant location.- Basic principles of engineering plant design: process evaluation and selection, process flow diagram, material and energy balances, unit operations, sources of raw materials, uses.- Application of products, health, safety and environmental factors (illustrated through case examples of incidents/accidents involving manufacturing processes and plants). - Design project work in which students will work together in a team (with individual contributions) to design a chemical process plant. - The group supervisor will be responsible for the organisation and assessment of the project. - Students will meet with the supervisor on a regular basis to ensure good communications within the project. - Students will also attend a series of lectures and seminars dealing with relevant aspects of the planning, design and evaluation of the project.- Students will be responsible for the organisation and delivery of relevant aspects required in the project, as prescribed. Each individual student or team will be required to produce a project plan detailing the planning and execution of the project and a final report covering detailed technical design, process control, financial and environmental aspects of the project. Students will also be required to make a verbal presentation on their findings at the end of the project.- Application of HYSYS for flowsheeting, material and energy balance calculations and process simulations.

Objectives

On completion of this module, students should:
- have an understanding of the basic concepts surrounding the chemical process industry (including pharmaceutical and fine chemical processes), design and manufacturing;
- understand the fundamentals of process chemistry, chemical technology and engineering science that underpin the synthesis of chemical products together with their process development, engineering operations and plant design;
- be capable of demonstrating chemical route and process selection based on sound scientific and engineering data and arguments;
- be aware of the safety, environmental, logistical, financial and other aspects associated with a major design project;
- have experience of project organisation and management, particularly being able to work in design teams and to communicate effectively within the team;
- have acquired the necessary skills to enable them to conduct a project with a significant degree of engineering competence;
- be capable of disseminating their findings in written and verbal form.

Learning outcomes
- Knowledge of research and development of chemical manufacture, particularly fine chemical and pharmaceutical manufacture, together with training of fundamental engineering design and practice.
- Principles of process chemistry and mass/energy balances for complex processes with chemical reactions and recycles including:
Methodologies for design of process equipment;
Environmental and safety issues;
Project management and cost analysis.
- Ability to apply HYSYS software for flow sheeting and process design.

Syllabus

- Process chemistry
- Process engineering calculations
- Chemical technology
- Methods for route selection
- Health, safety and environmental factors
- Design project including individual and group components
- Application of HYSYS for process calculations and simulations.

Teaching methods

Delivery type	Number	Length hours	Student hours
Group learning	22	4.50	99.00
Lecture	11	2.00	22.00
Seminar	2	1.00	2.00
Tutorial	15	1.00	15.00
Private study hours			162.00
Total Contact hours			138.00
Total hours (100hr per 10 credits)			300.00

Private study

40 hours for preparation of coursework exercises
122 hours for basic research supportive design project exercise.

Opportunities for Formative Feedback

Through coursework exercises and via regular tutorials and design project meetings.

Methods of assessment

Coursework

Assessment type	Notes	% of formal assessment
Presentation	Oral presentation	10.00
Group Project	Group project	40.00
Assignment	Assignment	15.00
Total percentage (Assessment Coursework)		65.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Exams

Exam type	Exam duration	% of formal assessment
Standard exam (closed essays, MCQs etc) (S2)	2 hr	35.00
Total percentage (Assessment Exams)		35.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading list

The reading list is available from the Library website

Last updated: 22/02/2017

Disclaimer

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• Undergraduate module catalogue
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• Taught Postgraduate programme catalogue

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