2017/18 Undergraduate Module Catalogue

CHEM3456 Lab Work with Integrated BSc Project (Medicinal)

35 creditsClass Size: 15

Module manager: Dr S A Gorman
Email: s.a.gorman@leeds.ac.uk

Taught: Semesters 1 & 2 (Sep to Jun) View Timetable

Year running 2017/18

Pre-requisite qualifications

Level 2 in Medicinal Chemistry or equivalent

This module is mutually exclusive with

CHEM3416

Lab Work with Integrated BSc Project

This module is not approved as a discovery module

Module summary

Students utilize research skills training gained in the previous two years of practical modules to:(i) undertake a selection of experiments in the organic and medicinal chemistry laboratories appropriate to the level 3 theory modules and to the general development of good laboratory technique.(ii) acquire, develop and apply research and evaluation skills by undertaking an extended project in semester 2. Apply their knowledge and understanding in order to initiate and carry out an extended piece of work or project.The module is designed to incorporate key requirements as outlined by the RSC in accreditation of chemistry degree programmes.

Objectives

On completion of this module students will have:
- undertaken advanced experimental work, with due attention to safety, in the chemical laboratory;
- manipulated advanced apparatus and record data for subsequent analysis;
- synthesized medicinal molecules of some structural complexity;
- competently handled air-sensitive materials and used them safely in synthetic methods;
- determined structure using spectroscopic data;
- undertaken advanced independent experimental work, with due attention to safety, and demonstrate the ability to write clear, scientific reports
- understood the aims, nature and methodology of a chemistry-related extended experiment;
- experienced the design and implementation of an investigation into a chemical problem using modern experimental techniques;
- developed an awareness of the nature of investigative chemistry, and the ability to interpret and present experimental evidence;
- developed their practical and problem solving skills.

Learning outcomes
The practical component of the core experiments incorporates the following themes, and students completing the module will be able to demonstrate:

(a) confidence in safely handling reagents/solvents, including those that are air-sensitive and/or pose significant hazards;
(b) ability to undertake advanced experimental work, with due attention to safety;
(c) ability to manipulate advanced laboratory apparatus and record data for subsequent analysis;
(d) ability to synthesize medicinal molecules of some structural complexity;
(e) determine structure using spectroscopic data;
(f) an understanding of the most common practical techniques and their proper application in the laboratory situation;
(h) a comprehensive knowledge and understanding of the major areas of synthetic chemistry.
(i) a knowledge of current techniques and methodologies appropriate to synthetic chemistry, with hands on practical experience of some of these

Students completing the integrated project will be able to demonstrate:
(a) a detailed appreciation of some specialist areas through research-based learning, reflecting the research expertise within the School;
(b) an ability to analyze, interpret and evaluate data; acquire and integrate information, and use information to solve problems;
(c) effective communication through a variety of media;
(d) the necessary transferable skills for further academic study or to pursue a career in a variety of occupations, namely:

- demonstrate a conceptual understanding which enables the development and sustaining of an argument;
- analyze and interpret particular aspects of recent research and/or scholarship; appreciate the uncertainty, ambiguity and limitations of knowledge in chemistry;
- present data in a coherent, structured manner through the preparation of a project report;
- and adopt a scientific approach to report writing.

Syllabus

During semester 1 students will undertake a selection of experiments in the areas of organic and medicinal chemistry, appropriate to the level 3 theory modules and designed for the general development of investigative laboratory techniques.

During semester 2 students will undertake an extended research project which will provide them with a more detailed understanding of some specialist areas through research-based learning, reflecting the research expertise within the University. This may take the form of either a laboratory based research project or a hypothesis-driven non laboratory-based project in a subject area of relevance to areas of expertise within the School. Students will apply and further develop their skills to define, refine, plan, implement and complete a relevant project in a timely manner. They will communicate project outcomes effectively by oral and written assessment methods.

Teaching methods

Delivery type	Number	Length hours	Student hours
Laboratory	33	3.00	99.00
Independent Learning	33	3.00	99.00
Private study hours			152.00
Total Contact hours			198.00
Total hours (100hr per 10 credits)			350.00

Private study

Students will spend semester 2 working on their project with their supervisor, conducting independent learning in the field of their project in private.

Opportunities for Formative Feedback

Continuous assessment of experimental reports provided on a one to one basis with a member of staff. Project feedback though regular meetings with project supervisor.

Methods of assessment

Coursework

Assessment type	Notes	% of formal assessment
Practical Report	Using standard laboratory report format	40.00
Project	Project initial report (500 words)	5.00
Project	Project final report (3000-5000 words)	30.00
Poster Presentation	Project poster presentation	10.00
Practical	Project performance based on observation by supervisor	15.00
Total percentage (Assessment Coursework)		100.00

The overall project mark will be based on the project report and the ability of the student to demonstrate research investigative skills in the practical element of the project. Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated.

Reading list

There is no reading list for this module

Last updated: 20/09/2016

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