2017/18 Undergraduate Module Catalogue

CAPE3701 Biomaterials and Applications

10 creditsClass Size: 50

Module manager: Dr G M Kale
Email: G.M.Kale@leeds.ac.uk

Taught: Semester 2 (Jan to Jun) View Timetable

Year running 2017/18

This module is mutually exclusive with

CAPE5701M

Biomaterials and Applications

Module replaces

PEME3710 Biomaterials and Applications

This module is not approved as a discovery module

Objectives

The main objectives of this research led module are:
- To apply the knowledge of physico-chemical properties of materials for the selection of materials as implants in the body as a service environment;
- To understand the performance of materials (metals, ceramics, polymers, composites) in body environment;
- To understand the concepts of biosensors and ceramic coatings.

Learning outcomes
The students will gain knowledge and understanding of the requirements of materials and their stability in a biological environment. Relevance of this to materials selection, design and properties of medical implants and devices and to understand the biological processes will be demonstrated.

More specifically, students should have gained an in-depth understanding of:
- the body as a service environment and the interactions between biomaterials and biological systems;
- the properties and requirements for biomaterials to be used in a range of applications within the body;
- the historical development of prostheses and reconstructive surgery and the part played by biomaterials development;
- the application of materials science in the design of biomaterials and dental materials;
- principles and design of biosensors for common biomarkers;
- the types of materials currently used, their processing and structure-property relationships and in-service performance, and promising future developments;
- biomineralisation - process and application;
- synthesis, characterization and application of hydroxyapatite as biomaterial;
- Engineered nanoparticles - biological uptake and implications.

Syllabus

This is a research led module and the specific topics to be covered include:
- Biocompatibility
- Degradation of metals in body environment
- Degradation of polymers in body environment
- Degradation of ceramics in body environment
- Biosensors and biomarkers
- Lipid-peptide interaction
- Antibacterial materials
- Antifungal and sporocidic materials
- Biomineralisation
- Hydroxapatite powders: hydrothermal synthesis; fluoropapatite
- Co-precipitation and sol-gel synthesis of hydroxyapatite powders
- Applications of hydroxyapatite powders; particle design
- Hydroxyapatite coatings; plasma coating; sol-gel and other methods
- Properties and applications of hydroxyapatite coatings
- Nanoparticles synthesis, applications and toxicology.

Teaching methods

Delivery type	Number	Length hours	Student hours
Lecture	22	1.00	22.00
Private study hours			78.00
Total Contact hours			22.00
Total hours (100hr per 10 credits)			100.00

Private study

Review of lecture notes each week
Directed reading supporting lectures
Preparation of essays
Revision for tests

Opportunities for Formative Feedback

4 x assessed coursework in the form of essay on selected topics
Class tests

Methods of assessment

Coursework

Assessment type	Notes	% of formal assessment
In-course Assessment	Test 4	10.00
In-course Assessment	Test 1	10.00
In-course Assessment	Test 2	10.00
In-course Assessment	Test 3	10.00
Essay	Essay 1 - 1,500 words maximum	15.00
Essay	Essay 2 - 1,500 words maximum	15.00
Essay	Essay 3 - 1,500 words maximum	15.00
Essay	Essay 4 - 1,500 words maximum	15.00
Total percentage (Assessment Coursework)		100.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading list

The reading list is available from the Library website

Last updated: 26/04/2017

Disclaimer

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