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2017/18 Taught Postgraduate Module Catalogue

CHEM5126M Organic Synthesis for Fine Chemical and Pharmaceutical Synthesis

15 creditsClass Size: 35

Module manager: Professor J Blacker
Email: j.blacker@leeds.ac.uk

Taught: Semester 1 (Sep to Jan) View Timetable

Year running 2017/18

Pre-requisite qualifications

Level 3 of any MChem programme in Chemistry or equivalent

This module is not approved as an Elective

Module summary

Fundamentals of organic synthesis to enable students to appreciate the key reactions used in the synthesis of fine chemicals and pharmaceuticals.

Objectives

To give students knowledge of the required range of organic chemistry and synthetic transformations needed to understand fine chemical and pharmaceutical synthesis.

Learning outcomes
Knowledge of organic synthesis, and its application in fine chemical and pharmaceutical manufacture.


Syllabus

- Revision of organic chemistry fundamentals, including bond formation, bond types, hybridisation, functional groups, and reaction types and mechanisms.
- Overview of available synthetic methods including, C-C bond formations, C-X bond formations, heterocycle synthesis, functional group interconversions, oxidation/reduction, the chemistry of carbonyl compounds, and retrosynthetic analysis.
- Useful reactions which will be encountered in subsequent modules, eg alkylations, Grignard, Friedel-Crafts, Pd-catalysed couplings, amide bond formation, reductive amination, alkene functionalisation.
- Principles of asymmetric synthesis and resolution.

Teaching methods

Delivery typeNumberLength hoursStudent hours
Class tests, exams and assessment12.002.00
Lecture201.0020.00
Tutorial21.002.00
Private study hours126.00
Total Contact hours24.00
Total hours (100hr per 10 credits)150.00

Private study

- 2 hour digestion of lecture material = 40 hours
- 2 hour background reading per lecture = 40 hours
- 4 hours completing each tutorial sheet = 8 hours
- Pre-exam revision = 38 hours.

Opportunities for Formative Feedback

Formative feedback during tutorials

Methods of assessment


Coursework
Assessment typeNotes% of formal assessment
Tutorial PerformanceOne hour block10.00
Tutorial PerformanceOne hour block10.00
Total percentage (Assessment Coursework)20.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated


Exams
Exam typeExam duration% of formal assessment
Standard exam (closed essays, MCQs etc)2 hr 00 mins80.00
Total percentage (Assessment Exams)80.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading list

There is no reading list for this module

Last updated: 05/11/2013

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