2017/18 Undergraduate Module Catalogue

DSUR2220 Introduction to Biomedical Sciences

20 creditsClass Size: 96

Module manager: Professor Steve Brookes
Email: s.j.brookes@leeds.ac.uk

Taught: Semesters 1 & 2 (Sep to Jun) View Timetable

Year running 2017/18

Pre-requisites

DSUR1126	Induction
DSUR1127	Health and Health Promotion
DSUR1128	Intro to the Oral Environment
DSUR1129	Oral Diseases, Def. & Repair 1
DSUR1130	Anxiety and Pain Management
DSUR1131	Personal & Professional Dev. 1
DSUR1132	Clinical Practice & Outreach 1

Co-requisites

DSUR2115	Oral Diseases, Defence and Repair 2
DSUR2117	Clinical Skills A
DSUR2118	PPD2
DSUR2119	Clinical Practice and Outreach 2
DSUR2122	Social Sciences Related to Dentistry

Module replaces

This module merges the previous modules of Introduction to Human Systemic Disease and Nutrition and Metabolism.

This module is not approved as a discovery module

Objectives

The module objective is to provide students with an introduction to biomedical science with a focus on the biological basis of health and disease. The aim is to equip students with sufficient knowledge and interest to help them further develop a good understanding of the fundamental biological basis of health and disease so that they are able to better understand disease aetiology and mechanism and be better informed to advise patients on a range of wider health and disease issues. There is a huge amount of misinformation around disease aetiology available on line and in the media and examples of this will be highlighted to emphasise the importance of critical appraisal and the need for an evidence base.

Learning outcomes
- Understand the basic principles of general pathology relevant to module content
- Describe the anatomy and histology of the GIT.
- Understand the metabolic functions of the liver.
- Understand major metabolic systems and how they are integrated.
- Understand how metabolism adapts to maintain homeostasis (fed & fasting states)
- Understand how dietary components are digested, transported, absorbed and stored.
- Understand the molecular and cellular disturbances associated with selected disease states.
- Understand the role of specific nutrients in health and disease.
- Understand the role of obesity in disease and appreciate the psychology of eating disorders.
- Appreciate the importance of nutrition in odontogenic development and maintaining oral health.
- Appreciate the molecular basis of cancer and the role of environment and diet in cancer.
- Understand the components of blood and demonstrate insight into abnormal clotting disorders.
- Appreciate insight into infective endocarditis, atherosclerosis, thrombosis and embolism.
- Demonstrate insight into acute and chronic inflammation in health and disease.
- Demonstrate insight into proteopathic disease especially in relation to amelogenesis imperfecta.
- Demonstrate insight into blood borne viruses.
- Demonstrate insight into sterilisation and disinfection of instruments

Skills outcomes
The skills acquired readily conform to the LeedsforLife Skills Map (especially with regard to planning and organisation, analytical skills, research skills, critical thinking, independent working and time management).

Syllabus

- Module Introduction
-The Anatomy and Functioning of the Digestive Tract
- Absorption and Transport of Dietary Lipids
- Introduction to Anabolism, Catabolism and Metabolism
- Catabolism of Glucose & Catabolism of Pyruvate
- Electron transport and oxidative phosphorylation
- Catabolism of Fatty Acids
- Glycogen metabolism
- Gluconeogenesis
- Synthesis of fatty acids
- Transport of Endogenously Synthesised Lipids (LDLs and CHD).
- Pentose Phosphate Pathway
- Amino acid metabolism
- Carbohydrate digestion, absorption and blood sugar homeostasis
- Endocrine Control of Fuel Utilization in Fasting and Fed States
- Obesity and diabetes
- Vitamin D and Calcium Homeostasis and Biomineralisation
- Vitamin C
- Folate acid and Vitamin B12
- Eating disorders
-Concept of a balanced diet (including dietary reference values, energy requirements and BMR).
-Vitamins A, E and B6
-Sodium, potassium, chloride and water; Iron; Iodine; Magnesium; Manganese; Zinc and Copper and Selenium.
- Physiology of blood
- Abnormal bleeding
- Bisphosphonates and bone
- Sterilisation and disinfection
- Blood borne viruses in dentistry
- Acute and chronic inflammation
- Atherosclerosis, thrombosis and embolism
- Nutrition and periodontal disease
- Nutrition and erosion
- Nutrition of caries
- Biology and molecular biology of cancer including environmental and nutritional factors
-Proteopathic diseases and amelogenesis imperfecta

Teaching methods

Delivery type	Number	Length hours	Student hours
On-line Learning	3	2.00	6.00
Lecture	38	1.00	38.00
Tutorial	2	1.00	2.00
Private study hours			154.00
Total Contact hours			46.00
Total hours (100hr per 10 credits)			200.00

Private study

The lectures should be regarded as a comprehensive but basic introduction to the subject. The lectures provide a foundation that will guide students towards further reading and that will enable them to consolidate their learning during private study periods. Approximately three quarters of the module credits are assigned to private study. Students will be advised, via the learning outcomes, of how and where they will benefit from additional reading and independent study to ensure a detailed understanding of the topic areas that can be subsequently used to inform clinical decision making.

Opportunities for Formative Feedback

Student progress will be formally assessed in the scheduled summative examinations.

Methods of assessment

Coursework

Assessment type	Notes	% of formal assessment
In-course MCQ	On-line formative MCQ exercises	0.00
Total percentage (Assessment Coursework)		0.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Exams

Exam type	Exam duration	% of formal assessment
Standard exam (closed essays, MCQs etc)	2 hr 00 mins	100.00
Total percentage (Assessment Exams)		100.00

EX1, SAQ/MC/MAQ/EMQ

Reading list

The reading list is available from the Library website

Last updated: 19/10/2017

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