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2019/20 Taught Postgraduate Module Catalogue

BIOL5171M Infectious & Non-infectious Diseases

10 creditsClass Size: 25

Module manager: Glenn A McConkey
Email: G.A.McConkey@leeds.ac.uk

Taught: Semester 1 View Timetable

Year running 2019/20

Pre-requisite qualifications

A first degree in chemical or biological sciences

Module replaces

Derives from BIOL5249M Host-Parasite Interactions and BIOL5264M Human Diseases with additional lectures from other level 5 modules that are to be discontinued.

This module is not approved as an Elective

Module summary

This module examines the molecular mechanisms responsible for inherited and infectious diseases and focuses on some of the most prevalent diseases burdening man. A critical analysis of the aetiology and interactions at the molecular level will provide a deep understanding of these diseases.

Objectives

The principal aim is to give introduction to exemplary pathogenic mechanisms for both inherited and infectious diseases. This will be achieved by delivering:

- An advanced tuition on the interaction of microbial pathogens with their hosts, with emphasis on new facets gleaned from genomics will be covered.
- Current understanding of molecular mechanisms in both the host and pathogen for viruses, fungi, and protozoan parasite infections
- Providing an up-to-date view on a spectrum of human disorders, focusing especially on the genetic and environmental factors underlying human disease.
- Introducing current research relating to mechanisms responsible for susceptibility and resistance to disease, chromosomal abnormalities and other conditions such as diabetes, ion-channel disorders, Alzheimer’s disease, and cancer.


On completion of this module, students should be able to:

- Describe in depth several microbial pathogens including viruses, fungi, and parasitic protozoa and their effects on hosts at the organismal, cellular, and molecular levels.
- Describe in depth the mechanisms underpinning a number of disorders such as Alzheimer's disease, diabetes and diseases related to ion channel malfunction.
- Critically appraise how host-parasite interactions impact pathogen detection and treatment.
- Comprehensively describe the hereditary basis of resistance and susceptibility to common infectious diseases.
- Apply bioinformatics to analyse these diseases and their interplay with the environment.

Learning outcomes
On completion of this module, students should:
- Be knowledgeable in several microbial pathogens including viruses, fungi, and parasitic protozoa and their effects on hosts at the organismal, cellular, and molecular levels.
- Possess an advanced understanding of human hereditary disorders and the molecular mechanisms underlying these disorders based on current research.
- Gain a critical understanding of how host-parasite interactions impact pathogen detection and treatment.
- Understand the mechanisms responsible for a number of disorders such as Alzheimer's disease, diabetes and diseases related to ion channel malfunction.
- Be introduced to the hereditary basis of resistance and susceptibility to common infectious diseases.
- Learned the application of bioinformatics to analyse these diseases and their interplay with the environment. This module seeks to enhance independent thinking and the ability to evaluate while encouraging teamwork and communication skills.

Skills outcomes
Opportunities for professional development, training and skill enhancement include time keeping and organizational skills through the preparation and delivery of course work for the data analysis exercises. Attendance, note-taking and participation in the demonstrations and also research seminars will also develop organizational and group working skills.


Syllabus

Lectures and discussions on a range of infectious and inherited pathogenic mechanisms. Infectious pathogens will include viruses, fungi, and parasitic protozoa. Hereditary disorders will include ion channels, cancer, neurodegeneration, and chromosomal abnormalities.

Teaching methods

Delivery typeNumberLength hoursStudent hours
Group learning31.334.00
Lecture121.0012.00
Private study hours84.00
Total Contact hours16.00
Total hours (100hr per 10 credits)100.00

Private study

Private study include reviewing online lecture material and associated reading material, critical analysis of research paper and reading around subject, and preparation for the group learning work and presentation.

Opportunities for Formative Feedback

Student progress will be monitored through the assessed critical analysis assignments and feedback provided.

Methods of assessment


Coursework
Assessment typeNotes% of formal assessment
Essay2 x critical analysis of research paper (1000 words each) (25% each)50.00
Group ProjectGroup presentation (5%), Individual report (45%)50.00
Total percentage (Assessment Coursework)100.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading list

There is no reading list for this module

Last updated: 30/04/2019

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