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2019/20 Taught Postgraduate Module Catalogue

CAPE5701M Biomaterials and Applications

15 creditsClass Size: 30

Module manager: Dr GM Kale
Email: g.m.kale@leeds.ac.uk

Taught: Semester 2 (Jan to Jun) View Timetable

Year running 2019/20

This module is not approved as an Elective

Objectives

The objectives of this research led module are as follows:
- To apply the knowledge of physico-chemical properties of materials for the selection of materials as implants in the body as a service environment;
- To understand the performance of materials (metals, ceramics, polymers, composites) in body environment;
- To understand the concepts of biosensors and ceramic coatings.

Learning outcomes
At the end of this module, students should gain knowledge and understanding of the requirements of materials and their stability in a biological environment. The relevance of this to materials selection, design and properties of medical implants and devices and to understand the biological processes will be demonstrated. More specifically, students should have gained an in-depth understanding of:
- the body as a service environment and the interactions between biomaterials and biological systems;
- the properties and requirements for biomaterials to be used in a range of applications within the body;
- the historical development of prostheses and reconstructive surgery and the part played by biomaterials development;
- the application of materials science in the design of biomaterials and dental materials;
- the principles and design of biosensors for common biomarkers;
- the types of materials currently used, their processing and structure-property relationships and in-service performance, and promising future developments;
- synthesis, characterisation and application of hydroxyapatite as biomaterial;
- engineered nanoparticles - their biological uptake and implications.


Syllabus

This is a research led module and the specific topics to be covered include:
- Biocompatibility;
- Degradation of metals in body environment;
- Degradation of polymers in body environment;
- Degradation of ceramics in body environment;
- Biosensors and biomarkers;
- Lipid-peptide interaction;
- Antibacterial materials;
- Antifungal and sporocidic materials;
- Hydroxapatite powders: hydrothermal synthesis; fluoropapatite;
- Co-precipitation and sol-gel synthesis of hydroxyapatite powders;
- Applications of hydroxyapatite powders; particle design;
- Hydroxyapatite coatings; plasma coating; sol-gel and other methods;
- Properties and applications of hydroxyapatite coatings;
- Nanoparticles synthesis, applications and toxicology.

Teaching methods

Due to COVID-19, teaching and assessment activities are being kept under review - see module enrolment pages for information

Delivery typeNumberLength hoursStudent hours
Lectures221.0022.00
Independent online learning hours22.00
Private study hours106.00
Total Contact hours22.00
Total hours (100hr per 10 credits)150.00

Private study

Independent on-line blended learning which consolidates and extends the lecture material and allows students to assess their progress via integrated quizzes;
Revision of lecture material in preparation for tests (20 hours);
Completion of worksheets and problem-based learning report (55 hours).

Opportunities for Formative Feedback

Performance in formative quizzes integrated into on-line learning resources and tests. Performance in essay submissions.

Methods of assessment

Due to COVID-19, teaching and assessment activities are being kept under review - see module enrolment pages for information


Coursework
Assessment typeNotes% of formal assessment
EssayEssay 1 - 1,500 words maximum20.00
EssayEssay 2 - 1,500 words maximum20.00
Total percentage (Assessment Coursework)40.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated


Exams
Exam typeExam duration% of formal assessment
Standard exam (closed essays, MCQs etc)2 hr 60.00
Total percentage (Assessment Exams)60.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading list

The reading list is available from the Library website

Last updated: 30/04/2019

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