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2021/22 Taught Postgraduate Module Catalogue

CHEM5601M Advanced Topics in Medicinal Chemistry 60 Credit

60 creditsClass Size: 120

Module manager: Dr Paul Thornton
Email: p.d.thornton@leeds.ac.uk

Taught: Semesters 1 & 2 (Sep to Jun) View Timetable

Year running 2021/22

Pre-requisite qualifications

Successful completion of Level 3 programme in Medicinal Chemistry

This module is mutually exclusive with

CHEM5600MAdvanced Topics in Chemistry 60 Credit
CHEM5602MAdvanced Topics in Chemical Biology (40 Credit)
CHEM5603MAdvanced Topics in Chemical Biology (30 Credit)
CHEM5604MAdvanced Topics in Chemistry (40 Credit)
CHEM5605MAdvanced Topics in Chemistry (30 Credit)
CHEM5606MAdvanced Topics in Chemistry (20 Credit)
CHEM5607MAdvanced Topics in Chemistry (10 Credits)
CHEM5608MAdvanced Topics in Chemistry (15 Credits)
CHEM5610MAdvanced Topics in Chemistry
CHEM5622MAdvanced Topics (10 Credits)

This module is not approved as an Elective

Objectives

On completion of the module, students will have an advanced level understanding of a wide range of chemistry, with a focus on medicinal chemistry, to the most advanced level. They will be able to demonstrate their knowledge and synthesis of multiple areas simultaneously and be able to explain and solve unseen problems of an advanced nature.

Ultimately the module will prepare them for postgraduate research either in academia or industry by providing the students with the core basis of advanced knowledge they will require. Through the continual assessment aspects of the module they will receive training in transferrable skills that will aid their future career.

Learning outcomes
The students will have a broad understanding of core areas of advanced chemistry and be able to solve unseen problem-led questions in these areas.

They will also be able to access the primary literature and use their knowledge to make a critical evaluation of this information.


Syllabus

The module will consist of 3 blocks, two assessed by exam and one by continuous assessment.

Block 1 (first semester) will consist of 6 topics and you will be required to answer unseen exam questions on 4 topics. The exact topic areas vary year by year to reflect research developments, but a representative list is:
- Medicinal Chemistry Strategy
- Expanding the Synthetic Chemistry Toolbox
- Characterising Structures and Mechanisms in Inorganic Chemistry
- Chemical Biology Tools
- The Combustion Chemistry of Biofuels
- Biomedical Applications of Polymeric Materials

Medicinal Chemistry Strategy and Expanding the Synthetic Chemistry Toolbox are compulsory topics.

Block 2 (second semester) will consist of 6 topics and you will be required to answer unseen exam questions on 4 topics. The exact topic areas vary year by year to reflect research developments, but a representative list is:
- Advanced Applications of Colorants
- Metals in Biology
- Heterocyclic Chemistry in Medicines and Natural Products
- Asymmetric and Stereoselective Synthesis
- Chemistry, Climate Change and Air Pollution: Atmospheric Measurements, Modelling and Policy

Heterocyclic Chemistry in Medicines and Natural Products and Asymmetric and Stereoselective Synthesis are compulsory topics.

For Block 3 (both semesters) there is a requirement to submit work corresponding to 4 topics. This block will be assessed by a portfolio of work (coursework). The exact topic areas vary year by year to reflect research developments, but a representative list is:
- Energy Transduction - Powering the Earth, Life and Society
- Nanomaterials
- Structural Control in Modern Materials
- Sustainability
- Structural Control in Modern Materials
- Physical Organic Chemistry
- Delivery of Functional Fluids
- Electronic Structure Calculations
- Case Studies in Pharmaceutical and Fine Chemical Synthesis
- Computational Drug Design
- Advanced Medicinal Chemistry
- Metals in Medicine

Computational Drug Design and Advanced Medicinal Chemistry are compulsory topics.

Teaching methods

Due to COVID-19, teaching and assessment activities are being kept under review - see module enrolment pages for information

Delivery typeNumberLength hoursStudent hours
Lectures1081.00108.00
Seminars121.0012.00
Private study hours480.00
Total Contact hours120.00
Total hours (100hr per 10 credits)600.00

Private study

Students will be presented with a wide range of advanced material and will be expected to spend considerable time consolidating this knowledge.

Additionally, they will be provided with practice problems that form the basis of the seminars for each topic. 

Reading for lectures and workshops
Reading research literature and preparation for coursework assignments
Preparation for examinations.


Opportunities for Formative Feedback

Formative exercises for workshops, and regularly-spaced online quizzes.

Methods of assessment

Due to COVID-19, teaching and assessment activities are being kept under review - see module enrolment pages for information


Coursework
Assessment typeNotes% of formal assessment
PortfolioElement 3. Each topic will involve one or more of the following types of coursework; Essay or Dissertation, Literature Review, Verbal Presentation. A student’s portfolio will depend upon the individual topics that students select for assessment.34.00
Total percentage (Assessment Coursework)34.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated


Exams
Exam typeExam duration% of formal assessment
Online Time-Limited assessment3 hr 00 mins33.00
Online Time-Limited assessment3 hr 00 mins33.00
Total percentage (Assessment Exams)66.00

Examined with all other Advanced Topics modules (CHEM5600M – CHEM5610M, as of February 2020). Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated.

Reading list

There is no reading list for this module

Last updated: 18/10/2021 10:53:44

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