Module and Programme Catalogue

Search site

Find information on

2021/22 Taught Postgraduate Module Catalogue

DSUR5138M Translation in Oral Systemic Diseases

15 creditsClass Size: 15

Module manager: Dr Josie Meade
Email: j.l.meade@leeds.ac.uk

Taught: Semester 2 (Jan to Jun) View Timetable

Year running 2021/22

Pre-requisite qualifications

Applicants must meet the programme entry requirements

This module is not approved as an Elective

Module summary

This module focuses on the rapidly expanding research interest in the associations between oral and systemic health. The aim is for students to gain an up to date and in depth view of the mechanisms linking oral and distant pathologies with relevance to translating research to the treatment of both oral and systemic human diseases.

Objectives

This module will explore the interplay between oral diseases and pathology at sites outside the oral cavity.

Students will gain an understanding of the multidisciplinary framework involved in studying the effects of oral disease on systemic health status and knowledge of the processes required to translate discoveries into changes in oral and systemic clinical practice.

Learning outcomes
1. Demonstrate expert knowledge of the clinically relevant biomedical science underpinning the risk associations, interactions and mechanisms that link oral and systemic diseases.
2. Apply mastery and expert knowledge of relevant research technologies and oral science to the field of oral and systemic cinical research.
3. Critically appraise scientific literature in related disease fields in order to identify areas of clinical need and potential societal impact.
4. Successfully combine all of the objectives above to synthesise relevant research questions and design the appropriate strategies to test them.
5. Prepare an extended essay that should be in the style of a publishable review article, and thus be of sufficient level to steer future translational research at the forefront of oral and systemic co-morbidity.

Skills outcomes
Draw together expert knowledge from multi-disciplinary fields of research to identify and understand common risks and potential mechanistic links between diseases.

To apply research skills to combined expert multidisciplinary knowledge to synthesise novel research questions and identify potential targets for therapeutic interventions for oral and systemic health.


Syllabus

The interactions between the human host and the microbiota in situations of oral health and disease involving oral microbial infections.

Oral and associated systemic pathologies.
- The aetiology of those oral diseases which are associated with systemic disease.
- Treatment of distant pathologies as a risk factor for oral disease.
- Shared risk factors and mechanistic links between oral and systemic diseases.

Genetic predisposition to oral disease, oral manifestations of genetic disorders and in the immunocompromised.

The use and development of biomarkers for both the prediction/ diagnosis of oral disease and oral biomarkers of systemic disease.

The evidence base and development of current and cutting edge treatments of oral and linked systemic diseases.

Unmet clinical needs and potential future treatments, interventions and frontier research directions based on the latest research currently at discovery, trials and meta-analysis stages.

Pathways and barriers to the translation of new research into impact on clinical practice and policy.

Teaching methods

Due to COVID-19, teaching and assessment activities are being kept under review - see module enrolment pages for information

Delivery typeNumberLength hoursStudent hours
Group learning23.006.00
Lecture91.009.00
Seminar22.004.00
Tutorial32.006.00
Private study hours125.00
Total Contact hours25.00
Total hours (100hr per 10 credits)150.00

Private study

Students will be expected to carry out preparative reading prior to each seminar, related to the specific content of each session. Students will be provided with a reading lists comprised largely of journal articles and reviews as fitting for Masters level learning. The reading will ensure all students attending the sessions will have reached a similar level of background knowledge allowing full participation. ~3 hrs per seminar.

Students will be expected to read scientific literature ready to appraise and discuss in tutorials. ~3 hrs preparation per tutorial.

Students will need private study and reading to consolidate and extend the learning guided by lectures.

Students will be expected to research and read widely from scientific literature to produce the formative presentation assessments and the extended essay assessment.

Opportunities for Formative Feedback

Student progress will be assessed through monitoring of student engagement and performance within seminars and tutorials.

The coursework assessment will take the form of a single project, assessed at multiple stages. The ultimate goal is to produce an extended structured essay detailing an area of clinical need and the research pathway required to fund, manage and deliver the desired health or societal impact.

Students will initially review literature in the field to identify a potential area of unmet clinical need. Students will present key literature within 'journal club' tutorials and receive peer to peer and tutor comment, providing the opportunity for early monitoring and formative assessment.

Students will then develop a brief outline of their coursework assessment and present this verbally. Presentations will contribute to formative assessment and provide an opportunity for feedback incorporation. Students will then further develop and expand their work to produce a final extended structured essay covering background, rationale, identifying appropriate methods, governance pathways and potential impact. This will provide the majority of the summative assessment for this module.

An online MCQ will be employed to ensure that students have developed expert knowledge across all the fields of disease covered within the module, not just the topic explored in great depth within an individual student's coursework.

Methods of assessment

Due to COVID-19, teaching and assessment activities are being kept under review - see module enrolment pages for information


Coursework
Assessment typeNotes% of formal assessment
EssayExtended essay 2500 words75.00
PresentationOutline Proposal0.00
Tutorial PerformanceJournal Club Tutorial0.00
Total percentage (Assessment Coursework)75.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated.


Exams
Exam typeExam duration% of formal assessment
Standard exam (closed essays, MCQs etc) 1 hr 25.00
Total percentage (Assessment Exams)25.00

Both components are non compensatable.

Reading list

The reading list is available from the Library website

Last updated: 11/05/2021 12:34:48

Disclaimer

Browse Other Catalogues

Errors, omissions, failed links etc should be notified to the Catalogue Team.PROD

© Copyright Leeds 2019