2024/25 Undergraduate Module Catalogue

BIOC2306 Intermediate Biochemistry

30 creditsClass Size: 100

Module manager: Dr Joan Boyes
Email: j.m.boyes@leeds.ac.uk

Taught: Semesters 1 & 2 (Sep to Jun) View Timetable

Year running 2024/25

Pre-requisite qualifications

Successful completion of Level 1 UG Programme - Biochemistry/ Medical Biochemistry.

Pre-requisites

BIOC1301	Introductory Integrated Biochemistry: the Molecules and Proc
BIOC1302	Introductory Biochemistry: Practical Skills
BIOC1303	Introductory Biochemistry: Problem Solving and Data Handling

Module replaces

BIOC2301: Intermediate Integrated Biochemistry, 60 credits, S3

This module is not approved as a discovery module

Objectives

The module builds upon the introductory biochemistry of molecules, pathways and cells studied at level one.

Learning outcomes
On completion of this module, students will have developed knowledge and extended further their understanding along the following major themes:
1. Protein Structure and Function Theme (Semester 1)
2. Genes Theme (Semester 2)

Syllabus

Semester 1
Protein Structure and Function Theme:
Ligand binding
Structural biology techniques including:
· mass spectrometry
· X-ray crystallography
· electron microscopy
· NMR
· AFM
Enzyme kinetics
Protein folding
Function of chaperones
Antibody structure and function
Use of antibodies in molecular biology
RNA biology
Bacterial infections

Semester 2
Genes Theme:
Eukaryotic gene expression including
· Epigenetics
· Transcription factors and their modifications
· Long range regulatory elements
Bioinformatics in relation to gene regulation
The cell cycle
Genetic diseases and therapy including:
· Genome organisation
· forensic analysis
· molecular diagnosis
- gene therapy
V(D)J recombination
Molecular biology of cancer

Teaching methods

Delivery type	Number	Length hours	Student hours
Class tests, exams and assessment	1	1.50	1.50
Class tests, exams and assessment	1	2.50	2.50
Class tests, exams and assessment	2	1.00	2.00
Lecture	60	1.00	60.00
Independent online learning hours			234.00
Private study hours			0.00
Total Contact hours			66.00
Total hours (100hr per 10 credits)			300.00

Private study

Online learning resources for use in student's own time. Revision packages with various practice questions and essay examples.

Opportunities for Formative Feedback

- Student attendance at lectures will be monitored in line with standard faculty practice.
- Completion of coursework assessment and exam.
- Engagement with VLE resources.

Methods of assessment

Coursework

Assessment type	Notes	% of formal assessment
In-course MCQ	Protein Structure & Function Theme (S1)	10.00
In-course MCQ	Genes Themes (S2)	10.00
Total percentage (Assessment Coursework)		20.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Exams

Exam type	Exam duration	% of formal assessment
Online Time-Limited assessment	2 hr 00 mins	30.00
Unseen exam	1 hr 20 mins	17.50
Online Time-Limited assessment	2 hr 00 mins	15.00
Unseen exam	1 hr 00 mins	17.50
Total percentage (Assessment Exams)		80.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading list

The reading list is available from the Library website

Last updated: 29/04/2024 16:10:35

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