2024/25 Undergraduate Module Catalogue
BLGY3153 Advanced Topics in Human Genetics and Epigenetics
20 creditsClass Size: 100
Module manager: Dr Stephanie Wright
Email: s.c.wright@leeds.ac.uk
Taught: Semester 1 (Sep to Jan) View Timetable
Year running 2024/25
Pre-requisite qualifications
Some genetics at Level 1.Module replaces
BLGY3152This module is not approved as a discovery module
Objectives
Students should gain understanding of current research in a range of topics in human genetics.Learning outcomes
On completion of the module, students will be able to;
- demonstrate detailed subject knowledge - demonstrate a conceptual understanding that enables the development of an argument;
- appreciate the limitations of knowledge in human genetics;
- apply their knowledge and understanding to carry out an extended piece of work or project;
- use the transferable/key/generic skills necessary for employment related to human genetics;
There will be a combination of live lectures and recorded videos that have been specifically adapted for online delivery. There will also be live sessions for discussion of specific research papers. Student understanding will be assessed continuously throughout the course, both through these sessions and via the assessed coursework. There will be timetabled sessions to provide coursework feedback.
Skills outcomes
The assessed coursework will provide experience in sourcing, selecting and interpreting data, and in presentation of logical arguments.
Syllabus
Topics covered:
- Telomeres: basic biology, inherited genetic disease, ageing and cancer;
- Epigenetics: epigenetic mechanisms in normal human physiology and disease, including cancer;
- DNA damage, repair and recombination, including mechanisms leading to genome instability;
chromosome syndromes, molecular cytogenetics, stratified medicine.
- Recombination and generation of diversity in the immune system;, including in cancer;
- Cancer genomes, including mutagenic processes, mutational signatures, epigenetics, targeted therapies, tumour evolution;
- Clinical aspects: , including chromosome syndromes, molecular cytogenetics, prenatal diagnosis, cancer cytogenetics, stratified medicine, molecular genetic diagnosis and examples of genetic testing.
Teaching methods
| Private study hours | 168.00 | ||
| Total Contact hours | 0.00 | ||
| Total hours (100hr per 10 credits) | 168.00 | ||
Private study
- 168 hours consolidating lectures, online learning and coursework preparation.Opportunities for Formative Feedback
There will be one piece of assessed coursework.Methods of assessment
Coursework
| Assessment type | Notes | % of formal assessment |
| In-course Assessment | Essay | 33.00 |
| Total percentage (Assessment Coursework) | 33.00 | |
Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated.
Exams
| Exam type | Exam duration | % of formal assessment |
| Online Time-Limited assessment | 24 hr 00 mins | 67.00 |
| Total percentage (Assessment Exams) | 67.00 | |
Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated
Reading list
The reading list is available from the Library websiteLast updated: 03/05/2024
Browse Other Catalogues
- Undergraduate module catalogue
- Taught Postgraduate module catalogue
- Undergraduate programme catalogue
- Taught Postgraduate programme catalogue
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