2013/14 Undergraduate Module Catalogue

PEME3710 Biomaterials and Applications

10 creditsClass Size: 50

Module manager: Dr G M Kale
Email: G.M.Kale@leeds.ac.uk

Taught: Semester 1 (Sep to Jan) View Timetable

Year running 2013/14

Module replaces

PREN3761 Biomaterials & Tissue Engineering

This module is not approved as an Elective

Objectives

The main objectives of this research led module are as follows:
- To apply the knowledge of physico-chemical properties of materials for the selection of materials as implants in the body as a service environment;
- To understand the performance of materials (metals, ceramics, polymers, composites) in body environment;
- To understand the concepts of biosensors and ceramic coatings.

Learning outcomes
The students will gain knowledge and understanding of the requirements of materials and their stability in a biological environment. Relevance of this to materials selection, design and properties of medical implants and devices and to understand the biological processes will be demonstrated.

More specifically, students should have gained an in-depth understanding of:
- the body as a service environment and the interactions between biomaterials and biological systems;
- the properties and requirements for biomaterials to be used in a range of applications within the body;
- the historical development of prostheses and reconstructive surgery and the part played by biomaterials development;
- the application of materials science in the design of biomaterials and dental materials;
- principles and design of biosensors for common biomarkers;
- the types of materials currently used, their processing and structure-property relationships and in-service performance, and promising future developments;
- biomineralisation - process and application;
- synthesis, characterization and application of hydroxyapatite as biomaterial;
- Engineered nanoparticles - biological uptake and implications.

Syllabus

This is a research led module and the specific topics to be covered include:
- Biocompatibility
- Degradation of metals in body environment
- Degradation of Polymers in body environment
- Degradation of ceramics in body environment
- Biosensors and biomarkers
- Lipid-peptide interaction
- Antibacterial materials
- Antifungal and sporocidic materials
- Biomineralisation
- Hydroxapatite powders: hydrothermal synthesis; fluoropapatite
- Co-precipitation and sol-gel synthesis of hydroxyapatite powders
- Applications of hydroxyapatite powders; particle design
- Hydroxyapatite coatings; plasma coating; sol-gel and other methods
- Properties and applications of hydroxyapatite coatings
- Nanoparticles synthesis, applications and toxicology

Teaching methods

Delivery type	Number	Length hours	Student hours
Class tests, exams and assessment	3	5.00	15.00
Lecture	22	1.00	22.00
Private study hours			63.00
Total Contact hours			37.00
Total hours (100hr per 10 credits)			100.00

Private study

Review of lecture notes each week
Directed reading supporting lectures
Revision for written exam
Writing coursework x 3

Opportunities for Formative Feedback

3 x assessed coursework in the form of essay on selected topics
1 x formal written exam

Methods of assessment

Coursework

Assessment type	Notes	% of formal assessment
Essay	1,000 words	15.00
Essay	1,000 words	15.00
Essay	1,000 words	10.00
Total percentage (Assessment Coursework)		40.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Exams

Exam type	Exam duration	% of formal assessment
Standard exam (closed essays, MCQs etc)	2 hr	60.00
Total percentage (Assessment Exams)		60.00

August resit only available for MEng students

Reading list

The reading list is available from the Library website

Last updated: 14/04/2014

Disclaimer

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