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2023/24 Taught Postgraduate Module Catalogue

REPR5230M Micromanipulation

15 creditsClass Size: 40

Module manager: Dr John Huntriss
Email: j.huntriss@leeds.ac.uk

Taught: 1 Jan to 31 May, 1 Sep to 31 Jul View Timetable

Year running 2023/24

Pre-requisite qualifications

Attendance at REPR5210M, REPR5220M.

Pre-requisites

REPR5210MFund. of Clinical Embryology
REPR5220MIVF and Embryo Culture

Co-requisites

REPR5160MResearch in Reproduction, Embryology & Assisted Reproduction
REPR5240MCryobiology & Cryopreservation
REPR5250MEthics & Law for Embryologists
REPR5260MRes. Proj: Clinical Embryology

This module is not approved as an Elective

Objectives

On completion of this module, students should be able to:
- critically discuss the importance of assisted fertilisation techniques;
- critically assess the techniques required to perform micromanipulation for assisted fertilisation, assisted hatching and embryo biopsy;
- describe and evaluate the theory, procedures and techniques relevant to Preimplantation Genetic Testing (PGT) including PGD and PGS.
- Understand the theory and practical application of stem cells, with particular relevance to artificial gametes.

Learning outcomes
On completion of this module students should be able to:
- Assess and evaluate the latest micromanipulation techniques and their risks and benefits to the patient;
- Have a comprehensive knowledge of Preimplantation Genetic Testing (PGT) including PGD and PGS, and an understanding of PGT services and modern genetic methods for PGT.
- Critically evaluate the epigenetic risks associated with the use of assisted reproduction and micromanipulation technologies and infertility itself.
- Identify and discuss the possible sources of epigenetic disruption arising from ART treatments and/or infertility.
- Discuss the derivation and uses of artificial gametes in fertility treatment.

Skills outcomes
Students will learn the latest micromanipulation techniques; their risks and benefits.
Students will learn how to provide a preimplantation genetic diagnosis service to appropriate patients.
Students will learn the epigenetic disorders resulting from the use of assisted reproduction techniques.


Syllabus

This module will concentrate on the new technologies now available in assisted reproduction. Students will learn the implications of new techniques and gain an appreciation of the equipment and skills involved. Existing and new technologies for micromanipulation, stem cell generation and use of preimplantation genetic diagnosis and their genetic and epigenetic consequences will be discussed and evaluated in relation to assisted conception procedures.

Teaching methods

Delivery typeNumberLength hoursStudent hours
On-line Learning501.0050.00
Lecture41.004.00
Practical13.003.00
Tutorial31.003.00
Private study hours90.00
Total Contact hours60.00
Total hours (100hr per 10 credits)150.00

Private study

Students will be expected to work in their own time researching online coursework and building their knowledge from the online materials.

Opportunities for Formative Feedback

Personal tutors are in regular, frequent contact with students by email, internet and telephone. Students have face-to-face tutorials to discuss current issues and questions, review progress and assess feedback, with early identification and support for students who are not achieving at a satisfactory level.

Methods of assessment


Coursework
Assessment typeNotes% of formal assessment
Essay1,500 words50.00
Total percentage (Assessment Coursework)50.00

The schedule for submission of the assessment for full-time MSc/PG Diploma Clinical Embryology and Assisted Reproduction Technology as detailed above is different to the schedule for submission of the assessment for the part-time MSc/PG Diploma Clinical Embryology due to the different schedule for delivery of the two programmes. For the part-time MSc/PG Diploma Clinical Embryology the essay will be set in S7 for submission in S13 of year 1 of study. Resits will be available for the coursework.


Exams
Exam typeExam duration% of formal assessment
OSCE (Objective Structured Clinical Exam)1 hr 00 mins50.00
Total percentage (Assessment Exams)50.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading list

The reading list is available from the Library website

Last updated: 11/05/2023

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