2015/16 Taught Postgraduate Module Catalogue
MATH5880M Statistics and DNA
15 creditsClass Size: 30
Module manager: Dr A Gusnanto
Email: A.Gusnanto@leeds.ac.uk
Taught: Semester 1 (Sep to Jan) View Timetable
Year running 2015/16
Pre-requisite qualifications
MATH2715 or MATH2735 or equivalent.This module is mutually exclusive with
MATH3880 | Introduction to Statistics and DNA |
This module is approved as an Elective
Module summary
Modern biological experiments produce large data sets involving information related to DNA. This module gives the basic biological background before looking at a range of data types and methods to analyse them.Objectives
To explore a range of statistical methods pertinient to the analysis of scientific data relating to DNA.Learning outcomes
To develop an understanding of
1. Molecular biology.
2. Analysis of evolutionary trees.
3. Statistical genetics.
4. Statistical modelling of microarrays.
5. Protein motifs and statistical models.
6. Forensic science and statistics.
Syllabus
1. Introduction to molecular biology
a) Introduction to cells, chromosomes and DNA
b) Cell division and inheritance
c) Genes, RNA and proteins
2. Evolutionary trees
a) Basic phylogenetic concepts
b) Maximum-parsimony tree construction
c) Distance-matrix tree construction
3.Statistical genetics
a) Basic concepts of genetics
b) Principles of Mendelian inheritance
c) Overview of genetic epidemiology
4. Statistical modelling of microarrays
a) Introduction to microarrays
b) Microarray data preparation
c) Identifying differentially expressed genes
5. Protein motifs and statistical models
6. Forensic science and statistics
Teaching methods
Delivery type | Number | Length hours | Student hours |
Lecture | 33 | 1.00 | 33.00 |
Practical | 1 | 2.00 | 2.00 |
Private study hours | 115.00 | ||
Total Contact hours | 35.00 | ||
Total hours (100hr per 10 credits) | 150.00 |
Private study
- Consolidating lecture material and further reading: 53 hours- Working on example sheets (6 sheets, 2 hours each): 12 hours
- Completing practical exercises: 30 hours
- Exam revision: 20 hours
Opportunities for Formative Feedback
Regular example sheets.Methods of assessment
Coursework
Assessment type | Notes | % of formal assessment |
Practical | 4 practicals | 20.00 |
Total percentage (Assessment Coursework) | 20.00 |
Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated
Exams
Exam type | Exam duration | % of formal assessment |
Standard exam (closed essays, MCQs etc) | 2 hr 30 mins | 80.00 |
Total percentage (Assessment Exams) | 80.00 |
Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated
Reading list
The reading list is available from the Library websiteLast updated: 16/04/2015
Browse Other Catalogues
- Undergraduate module catalogue
- Taught Postgraduate module catalogue
- Undergraduate programme catalogue
- Taught Postgraduate programme catalogue
Errors, omissions, failed links etc should be notified to the Catalogue Team.PROD