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2021/22 Undergraduate Module Catalogue

CHEM3455 Advanced Lab Work for MChem (Medicinal)

30 creditsClass Size: 40

Module manager: Dr Stephen Gorman
Email: s.a.gorman@leeds.ac.uk

Taught: Semesters 1 & 2 (Sep to Jun) View Timetable

Year running 2021/22

Pre-requisite qualifications

Level 2 in Medicinal Chemistry or equivalent

This module is not approved as a discovery module

Module summary

Students utilize research skills training gained in the previous two years of practical modules to:(i) undertake a selection of experiments in the organic and medicinal chemistry laboratories appropriate to the level 3 theory modules and to the general development of good laboratory technique.(ii) acquire, develop and apply research and evaluation skills by undertaking extended open-ended experiments. Apply their knowledge and understanding in order to initiate and carry out extended open-ended experiments.

Objectives

On completion of this module students will have:
- undertaken advanced experimental work, with due attention to safety, in the chemical laboratory;
- manipulated advanced apparatus and record data for subsequent analysis;
- synthesized medicinal molecules of some structural complexity;
- competently handled air-sensitive materials and used them safely in synthetic methods;
- determined structure using spectroscopic data;
- undertaken advanced independent experimental work, with due attention to safety, and demonstrate the ability to write clear, scientific reports
- understood the aims, nature and methodology of a chemistry-related extended experiment;
- experienced the design and implementation of an investigation into a chemical problem using modern experimental techniques;
- developed an awareness of the nature of investigative chemistry, and the ability to interpret and present experimental evidence;
- developed their practical and problem solving skills.

Learning outcomes
The practical component of the experiments incorporates the following themes, and students completing the module will be able to demonstrate:

(a) confidence in safely handling reagents/solvents, including those that are air-sensitive and/or pose significant hazards;
(b) ability to undertake advanced experimental work, with due attention to safety;
(c) ability to manipulate advanced laboratory apparatus and record data for subsequent analysis;
(d) ability to synthesize molecules of some structural complexity;
(e) determine structure using spectroscopic data;
(f) an understanding of the most common practical techniques and their proper application in the laboratory situation;
(h) a comprehensive knowledge and understanding of the major areas of synthetic medicinal chemistry.
(i) a knowledge of current techniques and methodologies appropriate to synthetic medicinal chemistry, with hands on practical experience of some of these.


Syllabus

Over the course of two semesters students will undertake a selection of extended experiments in the areas of organic and medicinal chemistry, appropriate to the level 3 theory modules and designed for the general development of investigative laboratory techniques.
They will communicate experiment outcomes effectively by oral and written assessment methods.

Teaching methods

Delivery typeNumberLength hoursStudent hours
Laboratory801.0080.00
e-Lecture61.006.00
Private study hours214.00
Total Contact hours86.00
Total hours (100hr per 10 credits)300.00

Private study

Students will spend both semesters working on their experimental reports, conducting independent learning in the field in private.

Opportunities for Formative Feedback

Feedback provided on experimental reports and online exercises.

Methods of assessment


Coursework
Assessment typeNotes% of formal assessment
PracticalAssessment of lab reports and skills plus online exercises100.00
Total percentage (Assessment Coursework)100.00

*To pass the module, students must achieve: an average mark of 40% or higher on the experimental part conducted in the Synthetic and Analytical Chemistry laboratory, and; an average mark of 40% or above on the experimental part conducted in the Physical Chemistry laboratory, and; an overall average mark of 40% or above.

Reading list

There is no reading list for this module

Last updated: 09/11/2021

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