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2020/21 Taught Postgraduate Module Catalogue

MEDP5317M Radionuclide Imaging

15 creditsClass Size: 30

Module manager: Dr Charalampos Tsoumpas

Taught: 1 Jan to 30 Jun View Timetable

Year running 2020/21

Pre-requisite qualifications

As per programme specification.

This module is mutually exclusive with

MEDP3517Radionuclide Imaging

This module is approved as an Elective

Module summary

It covers the physical, mathematical and computational aspects related to Radionuclide Imaging applied to Medicine and Biology for diagnostic and research proposes.


The aim of this module is to provide a deep understanding of the different scientific and technological aspects in radionuclide imaging and what are the relevant applications.

Learning outcomes
On completion of this module students should be able to:

1. Explain what is Radionuclide Imaging, what are its fundamental principles and how the field has evolved over the years
2. Identify, characterise and analyse critically the methods of radiopharmaceutical production for radionuclide imaging
3. Describe the basic physical interactions of gamma and beta radiation with matter
4. Assess and compare the use of different radiotracers in Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET)
5. Explain in detail the concept of image reconstruction and how it is utilised to obtain a 3D image using SPECT and PET
6. Provide comprehensive examples of clinical and preclinical use of radionuclide imaging
7. Understand what are dynamic PET and SPECT and why are they useful and place them in the context of other imaging modalities
8. Clarify and prioritise the key limitations of the existing techniques
9. Contextualise what molecular multiplex imaging is and how it helps advance the fields of medicine and biology

Skills outcomes
Use of Knowledge
Communication Skills
Medical Imaging
Radionuclide Imaging


Basic principles of radionuclide imaging;
Major breakthroughs in medical imaging with radionuclides;
Radiopharmaceutical production;
Interaction of ionising radiation with matter;
Composition of the nucleus and radioactive decay;
Radiation detectors and gamma photon counting systems;
SPECT and PET scanners and hybrid systems;
Image reconstruction in SPECT and PET;
Image processing, kinetic modelling and quantitative radionuclide imaging;
Clinical and preclinical applications of PET and SPECT;
New and future developments.

Teaching methods

Delivery typeNumberLength hoursStudent hours
On-line Learning12.002.00
Independent online learning hours50.00
Private study hours80.00
Total Contact hours20.00
Total hours (100hr per 10 credits)150.00

Private study

Students will be provided will pre lecture study materials which they will be expected to read to aid with their learning during formal lectures. They will also be expected to prepare materials for a poster presentation which will require independent online learning. Preparation for the examination will require private study of lecture materials and recommended reading texts. Furthermore, the students will be given two sets of formative multiple choice questions.

Opportunities for Formative Feedback

Student progress will be monitored through question and answer sessions which will take place at the beginning of each lecture or through formative MCQ exercises post lecture.

Student progress will also be monitored through tutorial session which will clarify any questions students have.

Methods of assessment

Assessment typeNotes% of formal assessment
Poster Presentation5 minutes in length plus 5 minutes of questions30.00
In-course MCQ2 x 1 hr sets of questions0.00
Total percentage (Assessment Coursework)30.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Exam typeExam duration% of formal assessment
Online Time-Limited assessment3 hr 00 mins70.00
Total percentage (Assessment Exams)70.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading list

The reading list is available from the Library website

Last updated: 30/06/2021 14:19:54


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