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2020/21 Undergraduate Module Catalogue

MEDI2222 Clinical Pathology

Module manager: Dr Richard Bishop

Taught: Semester 2 (Jan to Jun) View Timetable

Year running 2020/21

Pre-requisite qualifications

Successful completion of Year 1 MBChB


MEDI2201Control and Movement
MEDI2202Individuals and Populations 2
MEDI2217Research, Evaluation and Special Studies 2
MEDI2218Innovation, Development, Enterprise, Leadership and Safety 2
MEDI2219Campus to Clinic 2
MEDI2220RESS 2 Special Studies Project
MEDI2221Essential Medical Science
MEDI2222Clinical Pathology

Module replaces


This module is not approved as a discovery module


On completion of this module, students should be able to ...

1) Demonstrate knowledge of biochemistry, physiology, pathogenesis and anatomy so that it can be applied in the clinical setting to inform the investigation, diagnosis, management and monitoring of commonly occurring or important illustrative diseases.
2) Appreciate fully the principles of clinical pathology in order to effectively engage in clinical placement teaching in Yrs 3-5.
3) Identify the effective use of hospital pathology laboratories to justify the selection of tests and develop a critical attitude to their use.
4) Link their understanding to inform the diagnosis, management and treatment of patients and to control infection in the hospital environment.

Learning outcomes
The module is taught in the form of five separate strands; systematic pathology, microbiology and infection, haematology, clinical immunology and chemical pathology. By the end of the module students should be able to understand and describe:

1) Important and illustrative diseases as they relate to different organ systems within the body.
2) The aetiology, pathogenesis, diagnosis, treatment and prevention of infection.
3) Disorders of the cellular and non-cellular components of the blood.
4) The role of the immune system in disease.
5) The diagnosis of disease from the chemical changes that occur in tissues and fluids.

Skills outcomes
1) Basic histopathology.
2) Use and interpretation of clinical laboratory testing.


Students are provided with an integrated scientific and clinical understanding of disease through a consideration of the aetiology, pathogenesis, diagnosis, treatment and prevention of important diseases, based upon the disciplines of systematic pathology, microbiology, haematology, clinical immunology and chemical pathology.

Systematic Pathology

Alimentary system, cardiovascular system, respiratory system, breast, female genital system, male genital system, hepatobiliary system, bone and joint pathology, skin, urinary system, diseases seen in infants and children, central and peripheral nervous system, diseases of the head and neck, endocrine system.

Microbiology and Infection

Micro-organisms, host-pathogen relationships, diagnosis of infection, treatment of infection, infection prevention and control.


Physiology of blood, use of the laboratory, mechanisms of anaemia, thrombocytopenia, haematinic deficiency and the anaemia of chronic disease, thalassaemias and haemoglobinopathies, disorders of white cells, obstetric haematology, paediatric haematology, haemostasis overview, thrombosis, venous and arterial, inherited bleeding disorders, acquired bleeding disorders, blood groups and antibodies, safe and appropriate prescribing of blood products, complications of blood product transfusion, lymphadenopathy, Hodgkin and non-Hodgkin lymphomas, multiple myeloma and MGUS, acute and chronic leukaemias, myelodysplastic syndromes, myeloproliferative disorders.

Clinical Immunology

Immunodeficiency, autoimmunity and diagnosis of autoimmune disease, immunomodulation and immunosuppression, major histocompatibility complex and transplantation, allergy.

Chemical Pathology

Fluid and electrolyte balance, acid base disorders, calcium, phosphate, magnesium, bone and metabolism, enzymology, liver function, endocrine diseases, diabetes mellitus, gastrointestinal disease, inherited metabolic disorders and screening, lipid disorders, proteins - diagnostic uses, biochemical markers of central nervous system (CNS) diseases.

Teaching methods

Delivery typeNumberLength hoursStudent hours
Independent online learning hours80.00
Private study hours48.00
Total Contact hours91.00
Total hours (100hr per 10 credits)219.00

Private study

Private study and independent learning will allow students to reflect upon and apply the information and knowledge they have discussed and explored in the teaching sessions they have attended. Students will also have access to a wide range of online resources to support their learning. Students are expected to complete eight hours of private study and online learning per week.

Opportunities for Formative Feedback

Students will have one 60 minute tutorial every fortnight. The tutorials are designed to be interactive case presentations highlighting the weeks learning topics, and every student will be expected to contribute. Student progress will also be monitored through their performance in weekly online knowledge tests.

The assessment strategy on the MBChB programme is based upon regular opportunities for assessment for learning (formative) with regular feedback in order to build students confidence and monitor progress. Assessment for learning in this module will comprise 16 weekly on-line knowledge tests with instant feedback.

Methods of assessment

Exam typeExam duration% of formal assessment
Standard exam (closed essays, MCQs etc)4 hr 00 mins100.00
Total percentage (Assessment Exams)100.00

Normally resits will be assessed by the same methodology as the first attempt, unless otherwise stated

Reading list

The reading list is available from the Library website

Last updated: 09/09/2020 15:31:39


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